E-ISSN 2250-0944 | ISSN 2250-1150
 

Review Article 


Novel Concept of Drug Delivery Based on Chronotherapy: A Review

Devshree Pathak.

Abstract
Chronotropic drug delivery systems are drawing an increasing interest of the galvanic research in the field of
pharmaceuticals towards the development of more efficacious drug delivery systems for such diseases which pertains to a
well established oscillatory rhythm in their pathogenesis including hypertension, angina, asthma, cancer, arthritis, allergic
rhinitis, attention deficit syndrome, hypercholestremia, diabetes and many others. Currently, various approaches viz., single
unit, multiparticulate systems, electro-responsive pulsatile release, magnetically induced pulsatile release, systems with
different type of polymeric barrier coatings, stimuli sensitive etc. has been so far developed and characterized successfully.
Based on above approaches, recently novel formulations viz., PulsincapTM, TIMERx, CONTIN, OROS, CODAS,
DIFFUCAPS, CEFORM, etc. have also been envisaged by various researchers extensively. Pulsatile drug delivery systems
involve spatial and temporal release of the drug molecules after a predetermined lag time period. Sigmoid release profile can
be followed by these systems, which leads to maximisation of therapeutic effect and rapid drug release. The article on the
whole summarises the efficiency of such systems for diseases requiring safer, potential and holistic approaches respectively.

Key words: Circadian rhythm, Chronotherapy, Bioerodable systems, Pulsatile drug delivery, Electro-responsive system


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Devshree Pathak
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Devshree Pathak. Novel Concept of Drug Delivery Based on Chronotherapy: A Review. IJPRT. 2014; 4(2): 23-27. doi:10.31838/ijprt/04.02.05


Web Style

Devshree Pathak. Novel Concept of Drug Delivery Based on Chronotherapy: A Review. https://www.ijprt.org/?mno=302643694 [Access: March 03, 2023]. doi:10.31838/ijprt/04.02.05


AMA (American Medical Association) Style

Devshree Pathak. Novel Concept of Drug Delivery Based on Chronotherapy: A Review. IJPRT. 2014; 4(2): 23-27. doi:10.31838/ijprt/04.02.05



Vancouver/ICMJE Style

Devshree Pathak. Novel Concept of Drug Delivery Based on Chronotherapy: A Review. IJPRT. (2014), [cited March 03, 2023]; 4(2): 23-27. doi:10.31838/ijprt/04.02.05



Harvard Style

Devshree Pathak (2014) Novel Concept of Drug Delivery Based on Chronotherapy: A Review. IJPRT, 4 (2), 23-27. doi:10.31838/ijprt/04.02.05



Turabian Style

Devshree Pathak. 2014. Novel Concept of Drug Delivery Based on Chronotherapy: A Review. International Journal of Pharmacy Research & Technology, 4 (2), 23-27. doi:10.31838/ijprt/04.02.05



Chicago Style

Devshree Pathak. "Novel Concept of Drug Delivery Based on Chronotherapy: A Review." International Journal of Pharmacy Research & Technology 4 (2014), 23-27. doi:10.31838/ijprt/04.02.05



MLA (The Modern Language Association) Style

Devshree Pathak. "Novel Concept of Drug Delivery Based on Chronotherapy: A Review." International Journal of Pharmacy Research & Technology 4.2 (2014), 23-27. Print. doi:10.31838/ijprt/04.02.05



APA (American Psychological Association) Style

Devshree Pathak (2014) Novel Concept of Drug Delivery Based on Chronotherapy: A Review. International Journal of Pharmacy Research & Technology, 4 (2), 23-27. doi:10.31838/ijprt/04.02.05





Most Viewed Articles
  • Stability Indicating HPLC Method for Simultaneous Estimation of Nicotinamide and Salicylic Acid
    FALGUNI TANDEL, PRATIMA MORE
    IJPRT. 2018; 8(2): 43-47
    » Abstract » doi: 10.31838/ijprt/08.02.05

  • FORMULATION AND EVALUATION OF NANO PARTICULATE DRUG DELIVERY SYSTEM FOR AN EFFECTIVE TREATMENT OF ACNE
    ISHRAT S. CHHOWALA, DEVARSHI MADHUBHAI JANI, DR ABHAY DHARAMSI, DR. GAJANAN SHINDHE, DR. RAKESH PATEL.
    IJPRT. 2018; 8(2): 14-26
    » Abstract » doi: 10.31838/ijprt/08.02.02

  • Antimicrobial activities, antioxidant and phytochemical analysis of methanol and aqueous leaf extract of Phyllathus muellerianus (KUNTZ) Exell
    FRED COOLBORN AKHARAIYI* ,ABAYOMI OLABANJO DINA
    IJPRT. 2018; 8(1): 29-38
    » Abstract » doi: 10.31838/ijprt/08.01.04

  • Pharmacovigilance system and the future challenges in India-A Perspective
    *SANDHYA JAIN*, 1DR VIKAS JAIN, 2RADHA SHARMA
    IJPRT. 2018; 8(2): 27-31
    » Abstract » doi: 10.31838/ijprt/08.02.03

  • Piperine : A Bioenhancer
    Amar Singh*, Amar Deep
    IJPRT. 2011; 1(1): 1-5
    » Abstract » doi: 10.31838/ijprt/01.01.01

  • Most Downloaded
  • A case report on sympneumonic effusion
    Sandeep Akkam, Pooja dasari, Nandini Thota,
    IJPRT. 2021; 11(2): 17-18
    » Abstract » doi: 10.31838/ijprt/11.02.02

  • RELEASE KINETICS – CONCEPTS AND APPLICATIONS
    M. PADMAA PAARAKH , PREETHY ANI JOSE* , CM SETTY , G.V. PETER CHRISTOPER
    IJPRT. 2018; 8(1): 12-20
    » Abstract » doi: 10.31838/ijprt/08.01.02

  • FORMULATION AND EVALUATION OF ACTIVATED CHARCOAL PEEL OFF MASK
    SWETA V.KULKARNI*, DR.ARUN K.GUPTA, SHUBHAM BHAWSAR
    IJPRT. 2019; 9(2): 44-48
    » Abstract » doi: 10.31838/ijprt/09.02.06

  • Medicinal vegetal use by traditional healers in Ekiti State of Nigeria for diabetes treatment
    AKHARAIYI, FRED COOLBORN , ADEROBA ADEYEMI ADEGBEMISIPO
    IJPRT. 2018; 8(1): 21-28
    » Abstract » doi: 10.31838/ijprt/08.01.03

  • FORMULATION AND EVALUATION OF NANO PARTICULATE DRUG DELIVERY SYSTEM FOR AN EFFECTIVE TREATMENT OF ACNE
    ISHRAT S. CHHOWALA, DEVARSHI MADHUBHAI JANI, DR ABHAY DHARAMSI, DR. GAJANAN SHINDHE, DR. RAKESH PATEL.
    IJPRT. 2018; 8(2): 14-26
    » Abstract » doi: 10.31838/ijprt/08.02.02

  • Most Cited Articles
  • Piperine : A Bioenhancer
    Amar Singh*, Amar Deep
    IJPRT. 2011; 1(1): 1-5
    » Abstract » doi: 10.31838/ijprt/01.01.01
    Cited : 5 times [Click to see citing articles]

  • Biodiversity and conservation Ferns Diversity in different forests of Dehradun district
    CHHAYA SINGH, BRIJESH KUMAR, ANJU RANI, KAMLA DHYANI, RAJ SINGH
    IJPRT. 2017; 7(2): 01-07
    » Abstract » doi: 10.31838/ijprt/07.02.01
    Cited : 3 times [Click to see citing articles]

  • Stability Indicating HPLC Method for Simultaneous Estimation of Nicotinamide and Salicylic Acid
    FALGUNI TANDEL, PRATIMA MORE
    IJPRT. 2018; 8(2): 43-47
    » Abstract » doi: 10.31838/ijprt/08.02.05
    Cited : 3 times [Click to see citing articles]

  • A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient
    Dhiren P Shah*, Vineet C Jain, Hitesh P Dalvadi, Vinod D Ramani, Kajal G Patel, Mahesh G Saralai, Girish K Jani
    IJPRT. 2011; 1(1): 12-16
    » Abstract » doi: 10.31838/ijprt/01.01.03
    Cited : 2 times [Click to see citing articles]

  • EFFECT OF SEED EXTRACTS OF Elettaria cardamomum ON CALCIUM OXALATE CRYSTALLIZATION
    Manish A. Patel, Paras K. Patel, Dr. Avinash K Seth
    IJPRT. 2011; 1(1): 21-25
    » Abstract » doi: 10.31838/ijprt/01.01.05
    Cited : 2 times [Click to see citing articles]