Comparative Efficacy and Tolerability with Tirzepatide and Semaglutide in  Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Dr. Gaurav Rathee, Dr. Sudhir Kumar Atri, Dr. Anubha Garg, Dr.  Suman Roy, Dr. Mayank, Dr. Ankit Chahal

Comparative Efficacy and Tolerability with Tirzepatide and Semaglutide in Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Authors

Dr. Gaurav Rathee, Dr. Sudhir Kumar Atri, Dr. Anubha Garg, Dr. Suman Roy, Dr. Mayank, Dr. Ankit Chahal

Keywords:

Tirzepatide; Semaglutide; Obesity; Type 2 diabetes mellitus; Meta analysis.

Abstract

Obesity and type 2 diabetes mellitus(T2DM) are major global metabolicdisorders associated with substantialmorbidity and mortality. Incretin-basedtherapies have demonstrated significantbenefits in glycemic control and weight reduction

References

Aroda, V. R., Rosenstock, J., Terauchi, Y., Altuntas, Y., Lalic, N. M., Morales Villegas, E. C., ... & Haluzík, M. (2019). PIONEER 1: randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes. Diabetes care, 42(9), 17241732.

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Published

2026-04-23

How to Cite

Dr. Gaurav Rathee, Dr. Sudhir Kumar Atri, Dr. Anubha Garg, Dr. Suman Roy, Dr. Mayank, Dr. Ankit Chahal. (2026). Comparative Efficacy and Tolerability with Tirzepatide and Semaglutide in Obesity and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis . International Journal of Pharmacy Research & Technology (IJPRT), 16(1), 1874–1900. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1799