Study of Histopathological Lesions in Hysterectomy Specimens at Tertiary Care Hospital

Abstract

Background: Hysterectomy is one of the most commonly performed gynaecological surgical procedures for the management of various benign and malignant uterine conditions. Histopathological examination of hysterectomy specimens plays a vital role in confirming clinical diagnosis and identifying unsuspected lesions.

Materials and Methods: This retrospective and prospective observational cross-sectional descriptive study was conducted in the Department of Histopathology at Pravara Rural Hospital for 2 years duration. A total of 512 hysterectomy specimens received during the study period were analysed. Specimens were processed using standard histopathological techniques, stained with haematoxylin and eosin, and examined microscopically. Lesions of endometrium, myometrium, and cervix were classified according to Robbins Basic Pathology.

Results: Out of 9340 specimens received, 512 (5.48%) were hysterectomy specimens. The majority of patients were in the age group of 41–50 years (40.6%). Proliferative endometrium (56.83%) was the most common endometrial finding. Leiomyoma (26.56%) and adenomyosis (23.04%) were the predominant myometrial lesions. Chronic nonspecific cervicitis (91.4%) was the most frequent cervical lesion. Malignant lesions were relatively rare.

Conclusion: Most hysterectomy specimens showed benign histopathological lesions, highlighting the importance of routine histopathological examination for accurate diagnosis, detection of incidental lesions, and appropriate patient management.