Significance of Inj. Methylprednisolone in the Treatment of Visual Complaints in Acute Methanol Poisoning - A Case Series Study-Retrospective

Abstract

Background: Methanol poisoning is a life-threatening emergency. One of the most serious complications is visual impairment due to toxic optic neuropathy. Current treatments include ethanol/fomepizole, folinic acid, and dialysis. The role of corticosteroids like methylprednisolone is still debated. This study evaluates its significance in visual recovery.

Objective: To assess improvement in visual acuity following treatment with Inj. Methylprednisolone and to assess optic disc changes using Colour vision, fundus examination.

Method: This retrospective, non-comparative, intervention case series examines the ophthalmological data of patients diagnosed with methanol-induced optic neuropathy during illicit methanol poisoning tragedy at Govt. Kallakurichi medical college and hospital. Patients’ characteristics and the results of initial and final ophthalmological examinations were documented.

Result: Out of 145 patients, 8 were diagnosed with methanol-induced toxic optic neuropathy. They presented with severe bilateral visual loss and disc edema. Following corticosteroid therapy, all showed improvement in visual acuity, pupillary reflexes, colour vision, and fundus appearance

Conclusion: A timely diagnosis and treatment of patient with methanol-induced optic neuropathy is important to achieve a good visual prognosis.