Triple-Arm Randomized Trial of Intraperitoneal Levobupivacaine,  Dexmedetomidine, and Placebo for Analgesia After Laparoscopic  Cholecystectomy

Dr. Kumaragurubaran T. R., Dr. Rakesh Nongthombam, Dr. Ramkumar I.

Triple-Arm Randomized Trial of Intraperitoneal Levobupivacaine, Dexmedetomidine, and Placebo for Analgesia After Laparoscopic Cholecystectomy

Authors

Dr. Kumaragurubaran T. R., Dr. Rakesh Nongthombam, Dr. Ramkumar I.

Keywords:

pain, Laparoscopic cholecystectomy, intraperitoneal analgesia, levobupivacaine, dexmedetomidine

Abstract

Background: Pain after laparoscopic cholecystectomy is still a major clinical issue. The use ofanalgesic agents through intraperitoneal instillation may lead to better multimodal analgesia.The current research was aimed at comparing the analgesic effects of levobupivacaine and dexmedetomidine against placebo

References

Kim TH, Kang HK, Park JS, Chang IT, Park SG. Intraperitoneal ropivacaine instillation for postoperative pain relief after laparoscopic cholecystectomy. J Korean Surg Soc 2010;79:1306.

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Published

2026-01-12

How to Cite

Dr. Kumaragurubaran T. R., Dr. Rakesh Nongthombam, Dr. Ramkumar I. (2026). Triple-Arm Randomized Trial of Intraperitoneal Levobupivacaine, Dexmedetomidine, and Placebo for Analgesia After Laparoscopic Cholecystectomy . International Journal of Pharmacy Research & Technology (IJPRT), 16(1), 123–143. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1426