A Study of Thrombocytopenia in a Pregnancy at a Tertiary Care Centre

Abstract

Background: Thrombocytopenia is the second most common haematological abnormality after anaemia encountered in pregnancy. Thrombocytopenia is defined as the platelet count of less than 150,000/ml. Pregnancy causes varied alterations in hematopoietic systems. Thrombocytopenia is second only to anemia as the most common hematologic abnormality in pregnancy. It occurs commonly during pregnancy and accounts for around 7–8% of the all the pregnancies. The causes are accelerated platelet consumption or decreased production

Aim and Objectives: “A Study of thrombocytopenia in pregnancy at a tertiary care center.2. To study proportion of thrombocytopenia in pregnancy at a tertiary care center. 3. To study the association of thrombocytopenia with risk factors. 4. To study clinical profile of thrombocytopenia cases

Methodology: Study Design: Cross sectional study.

Study Setting: OBGY department of VDGMC Latur, Maharashtra.

Study Population: All pregnant women with Gestational age from 28weeks to 40weeks with thrombocytopenia in ANC Clinic of OBGY department of VDGMC Latur such cases were included in the study.

Study Period: 18months from 1 Dec 2023 to 1 July 2025.

Sample Size = 140

Results: Proportion of Thrombocytopenia among ANC Women was 1.64%, most of cases presented with mild thrombocytopenia 120 (85.71%).The majority of cases occurred in the 20–30 years age group (75 cases, 53.6%), the majority were multigravida (97 cases, 69.2%), thrombocytopenia was most frequently observed beyond >37 weeks (61 cases, 43.6%), majority of cases reported vegetarian diet pattern 94 (67.14%),majority of cases reported no H/O platelets transfusion 134 cases (95%) and 6 cases (5%) had a history of platelets transfusion. majority of cases diagnosed with platelet count between 120001-150000, 88 cases , 31 cases (22.1%) had identifiable risk factors associated with thrombocytopenia. The most frequent association was anaemia (12 cases, 8.6%), followed by non-severe preeclampsia/gestational hypertension (4 cases, 2.9%) and infections including dengue (4 cases, 2.9%). The association between risk factors and thrombocytopenia was statistically significant (p < 0.001).

Conclusions: The present study provides a comprehensive overview of thrombocytopenia in pregnancy, its prevalence, severity, and associated determinants in a tertiary care setting. The proportion of thrombocytopenia was 1.64%, which, though relatively low, represents a clinically important condition due to the maternal and fetal risks involved.