Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine

PRAVEEN ENDHARAPU; SOMNATH DE; VENU MADHAV KATLA

doi:10.31838/ijprt/13.02.11

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Research Article

IJPRT. 2023; 13(2): 101-114

doi: 10.31838/ijprt/13.02.11

Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA.

Abstract
Felodipine, a BCS class II calcium channel blocker, is utilized in the administration of hypertension and angina pectoris. Because of the unfortunate dissolvability and low bioavailability of the medication, there is a need to plan an elective course to accomplish a consistent plasma convergence of felodipine for its greatest remedial utility and can be accomplished by transdermal route.In this review, framework type transdermal patches were
arranged utilizing various blends of hydrophilic polymer, to be specific, polyvinylpyrrolidone (PVP) and hydrophobic polymer, in particular, ethyl cellulose (EC) by dissolvable dissipation procedure and were oppressed for characterization.The Fourier change infrared examinations affirmed the similarity among medication and polymers. The patches F1 to F7exhibited uniform weight going from 153.3mg to 242.6mg And thickness of F1 to F7 are going from 0.133 to 0.22mm. Among the different clusters, the consistency weight and thickness shows that the polymeric arrangement of the medication is all around scattered in the patches. Every one of the details (F1 to F7) showed genuinely uniform medication content going from 95.77% to 98.67% individually. it is obviously demonstrated that the Felodipine transdermal patches containing Eudragit RS 100 in the proportion of 1:2 (F6) was the best detailing among the pre-arranged patches.

Key words: Calcium channel blocker, Felodipine, Transdermal, Permeation

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Pubmed Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. IJPRT. 2023; 13(2): 101-114. doi:10.31838/ijprt/13.02.11

Web Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. https://www.ijprt.org/?mno=138287 [Access: March 01, 2023]. doi:10.31838/ijprt/13.02.11

AMA (American Medical Association) Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. IJPRT. 2023; 13(2): 101-114. doi:10.31838/ijprt/13.02.11

Vancouver/ICMJE Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. IJPRT. (2023), [cited March 01, 2023]; 13(2): 101-114. doi:10.31838/ijprt/13.02.11

Harvard Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA (2023) Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. IJPRT, 13 (2), 101-114. doi:10.31838/ijprt/13.02.11

Turabian Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. 2023. Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. International Journal of Pharmacy Research & Technology, 13 (2), 101-114. doi:10.31838/ijprt/13.02.11

Chicago Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA. "Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine." International Journal of Pharmacy Research & Technology 13 (2023), 101-114. doi:10.31838/ijprt/13.02.11

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

PRAVEEN ENDHARAPU, SOMNATH DE, VENU MADHAV KATLA (2023) Formulation Optimization And Evaluation Of Evaluation Of Transdermal Drug Delivery System Of Felodipine. International Journal of Pharmacy Research & Technology, 13 (2), 101-114. doi:10.31838/ijprt/13.02.11

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