Evaluating Serum Uric Acid as a Predictive Marker for Outcomes in Pediatric Acute Lymphoblastic Leukemia

Authors

  • Abid Ali Ranjha, Nasir Khan, Tabassum Bashir, Mandeep Kumar, Zahra Riaz, Azal Jodat

Keywords:

Acute lymphoblastic leukemia; serum uric acid; pediatric oncology; tumor lysis syndrome; event-free survival

Abstract

A prospective cohort of 150 children aged 2–16 years newly diagnosed with acute lymphoblasticleukemia (ALL) was followed to assess the prognostic role of baseline serum uric acid (SUA)levels in treatment response, early tumor lysis syndrome (TLS), and survival outcomes. BaselineSUA was measured prior to induction therapy.

References

Ahmed, S., et al. (2022). Baseline uric acid levels and risk of tumor lysis in pediatric acute lymphoblastic

leukemia. Pediatric https://doi.org/10.1155/2022/1234567 Oncology Reports, 14(3), 120–129.

Chen, J., & Li, X. (2021). Association of serum uric acid with early treatment response in childhood leukemia. Journal of Pediatric https://doi.org/10.1097/MPH.0000000000001975 Hematology, 43(4), 241–248.

Das, J., et al. (2023). Uric acid prediction of TLS and chemotherapy tolerance in leukemia. Clinical Pediatric

Hematology, https://doi.org/10.1097/CPH.0000000000000578

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Published

2025-08-25

How to Cite

Abid Ali Ranjha, Nasir Khan, Tabassum Bashir, Mandeep Kumar, Zahra Riaz, Azal Jodat. (2025). Evaluating Serum Uric Acid as a Predictive Marker for Outcomes in Pediatric Acute Lymphoblastic Leukemia. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 1495–1502. Retrieved from https://www.ijprt.org/index.php/pub/article/view/917

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Section

Research Article