PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF STEM BARK CRUDE EXTRACT OF Danielliaoliveri

GENDE; H.U. SALLAU; S. ABUBAKAR; H. YAKUBU

doi:10.31838/ijprt/10.02.06

Authors

GENDE Chemistry Department, Abubakar Tafawa Balewa University ,Bauchi, Bauchi State 740001, Nigeria
H.U. SALLAU Chemistry Department, Abubakar Tafawa Balewa University ,Bauchi, Bauchi State 740001, Nigeria
S. ABUBAKAR Chemistry Department, Abubakar Tafawa Balewa University ,Bauchi, Bauchi State 740001, Nigeria
H. YAKUBU Chemistry Department, Abubakar Tafawa Balewa University ,Bauchi, Bauchi State 740001, Nigeria

DOI:

https://doi.org/10.31838/ijprt/10.02.06

Keywords:

phytochemical, extraction, Danielliaoliveri

Abstract

This research seeks to explore the phytochemical screening and antioxidant activity of stem bark crude extract of Danielliaoliveri stembark. The stem bark of the plant was extracted using various solvents with varying polarities. Standard methods were adopted to screen antioxidant and phytochemical nature of the plant. The results of extraction revealed the following order of percentage recovery: 3.82 <7.62 < 14.12 < 87.50 obtained from petroleum ether, chloroform, ethyl acetate and aqueous extracts respectively. Results of phytochemical screening of various solvent extracts revealed the presence of saponins, terpenoids, alkaloids, phenols, flavonoids, steroids and tannins in the stem bark of the plant. The antioxidant activity of the crude fractions of stem bark of the plant ranged from 21.19± 1.54 (IC50 = 47.74 µg/ml) to 47.01± 0.98(IC50=21.29±0.44 µg/ml).The stem bark of the plant was found to contain good natural antioxidants. Hence it can be used for the treatment of inflammatory diseases, cardiovascular and diabetes.