Formulation and Evaluation of Buccal Patches of Timolol Maleate

VELPOOR DIVYA; G.S.VALLURI; G.VIJAY KUMAR

doi:10.31838/ijprt/13.02.06

2023, Vol: 13, Issue: 2

13 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Research Article

IJPRT. 2023; 13(2): 46-51

doi: 10.31838/ijprt/13.02.06

Formulation and Evaluation of Buccal Patches of Timolol Maleate

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR.

Abstract
The present investigation is concerned with the formulation and development of controlled release mucoadhesive buccal patch of Timolol maleate using natural and synthetic polymers. Timolol maleate is a non-selective beta-adrenergic blocker, and having short biological half-life, approximate 4.1 h, and low oral bioavailability. Therefore in order to control the release and increase the residence time these formulations are carried out. Natural polymer such as Chitosan and Synthetic polymers such as HPMC K15M and Eudragit RL100 were used to formulate the buccal patches. Various grades of Tween are used to increase the permeation capacity of the patch. All the formulations were evaluated for Weight Uniformity, Thickness, Folding Endurance, Swelling Index, Drug Content Uniformity, Tensile Strength and In vitro Drug Release. From all the prepared formulations, F6 showed good drug release characteristic. Drug release from the patches follows desire controlled release phenomenon as needed in buccoadhesive drug delivery.

Key words: Controlled release, Chitosan, Tween, Tensile strength

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by VELPOOR DIVYA Articles by G.S.VALLURI Articles by G.VIJAY KUMAR
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. Formulation and Evaluation of Buccal Patches of Timolol Maleate. IJPRT. 2023; 13(2): 46-51. doi:10.31838/ijprt/13.02.06

Web Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. Formulation and Evaluation of Buccal Patches of Timolol Maleate. https://www.ijprt.org/?mno=137817 [Access: March 01, 2023]. doi:10.31838/ijprt/13.02.06

AMA (American Medical Association) Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. Formulation and Evaluation of Buccal Patches of Timolol Maleate. IJPRT. 2023; 13(2): 46-51. doi:10.31838/ijprt/13.02.06

Vancouver/ICMJE Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. Formulation and Evaluation of Buccal Patches of Timolol Maleate. IJPRT. (2023), [cited March 01, 2023]; 13(2): 46-51. doi:10.31838/ijprt/13.02.06

Harvard Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR (2023) Formulation and Evaluation of Buccal Patches of Timolol Maleate. IJPRT, 13 (2), 46-51. doi:10.31838/ijprt/13.02.06

Turabian Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. 2023. Formulation and Evaluation of Buccal Patches of Timolol Maleate. International Journal of Pharmacy Research & Technology, 13 (2), 46-51. doi:10.31838/ijprt/13.02.06

Chicago Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. "Formulation and Evaluation of Buccal Patches of Timolol Maleate." International Journal of Pharmacy Research & Technology 13 (2023), 46-51. doi:10.31838/ijprt/13.02.06

MLA (The Modern Language Association) Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR. "Formulation and Evaluation of Buccal Patches of Timolol Maleate." International Journal of Pharmacy Research & Technology 13.2 (2023), 46-51. Print. doi:10.31838/ijprt/13.02.06

APA (American Psychological Association) Style

VELPOOR DIVYA, G.S.VALLURI, G.VIJAY KUMAR (2023) Formulation and Evaluation of Buccal Patches of Timolol Maleate. International Journal of Pharmacy Research & Technology, 13 (2), 46-51. doi:10.31838/ijprt/13.02.06

Most Viewed Articles

Stability Indicating HPLC Method for Simultaneous Estimation of Nicotinamide and Salicylic Acid
FALGUNI TANDEL, PRATIMA MORE
IJPRT. 2018; 8(2): 43-47
» Abstract » doi: 10.31838/ijprt/08.02.05

FORMULATION AND EVALUATION OF NANO PARTICULATE DRUG DELIVERY SYSTEM FOR AN EFFECTIVE TREATMENT OF ACNE
ISHRAT S. CHHOWALA, DEVARSHI MADHUBHAI JANI, DR ABHAY DHARAMSI, DR. GAJANAN SHINDHE, DR. RAKESH PATEL.
IJPRT. 2018; 8(2): 14-26
» Abstract » doi: 10.31838/ijprt/08.02.02

Antimicrobial activities, antioxidant and phytochemical analysis of methanol and aqueous leaf extract of Phyllathus muellerianus (KUNTZ) Exell
FRED COOLBORN AKHARAIYI* ,ABAYOMI OLABANJO DINA
IJPRT. 2018; 8(1): 29-38
» Abstract » doi: 10.31838/ijprt/08.01.04

Pharmacovigilance system and the future challenges in India-A Perspective
*SANDHYA JAIN*, 1DR VIKAS JAIN, 2RADHA SHARMA
IJPRT. 2018; 8(2): 27-31
» Abstract » doi: 10.31838/ijprt/08.02.03

Piperine : A Bioenhancer
Amar Singh*, Amar Deep
IJPRT. 2011; 1(1): 1-5
» Abstract » doi: 10.31838/ijprt/01.01.01

Most Downloaded

A case report on sympneumonic effusion
Sandeep Akkam, Pooja dasari, Nandini Thota,
IJPRT. 2021; 11(2): 17-18
» Abstract » doi: 10.31838/ijprt/11.02.02

RELEASE KINETICS CONCEPTS AND APPLICATIONS
M. PADMAA PAARAKH , PREETHY ANI JOSE* , CM SETTY , G.V. PETER CHRISTOPER
IJPRT. 2018; 8(1): 12-20
» Abstract » doi: 10.31838/ijprt/08.01.02

FORMULATION AND EVALUATION OF ACTIVATED CHARCOAL PEEL OFF MASK
SWETA V.KULKARNI*, DR.ARUN K.GUPTA, SHUBHAM BHAWSAR
IJPRT. 2019; 9(2): 44-48
» Abstract » doi: 10.31838/ijprt/09.02.06

Medicinal vegetal use by traditional healers in Ekiti State of Nigeria for diabetes treatment
AKHARAIYI, FRED COOLBORN , ADEROBA ADEYEMI ADEGBEMISIPO
IJPRT. 2018; 8(1): 21-28
» Abstract » doi: 10.31838/ijprt/08.01.03

Most Cited Articles

Piperine : A Bioenhancer
Amar Singh*, Amar Deep
IJPRT. 2011; 1(1): 1-5
» Abstract » doi: 10.31838/ijprt/01.01.01
Cited : 5 times [Click to see citing articles]

Biodiversity and conservation Ferns Diversity in different forests of Dehradun district
CHHAYA SINGH, BRIJESH KUMAR, ANJU RANI, KAMLA DHYANI, RAJ SINGH
IJPRT. 2017; 7(2): 01-07
» Abstract » doi: 10.31838/ijprt/07.02.01
Cited : 3 times [Click to see citing articles]

A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient
Dhiren P Shah*, Vineet C Jain, Hitesh P Dalvadi, Vinod D Ramani, Kajal G Patel, Mahesh G Saralai, Girish K Jani
IJPRT. 2011; 1(1): 12-16
» Abstract » doi: 10.31838/ijprt/01.01.03
Cited : 2 times [Click to see citing articles]

EFFECT OF SEED EXTRACTS OF Elettaria cardamomum ON CALCIUM OXALATE CRYSTALLIZATION
Manish A. Patel, Paras K. Patel, Dr. Avinash K Seth
IJPRT. 2011; 1(1): 21-25
» Abstract » doi: 10.31838/ijprt/01.01.05
Cited : 2 times [Click to see citing articles]

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access. The articles in International Journal of Pharmacy Research & Technology are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

Copyright � 2023 International Journal of Pharmacy Research & Technology All Rights Reserved. Subject to change without notice from or liability to International Journal of Pharmacy Research & Technology. For best results, please use Internet Explorer or Google Chrome	Contact Information International Journal of Pharmacy Research & Technology (IJPRT) C/O Advanced Scientific Research, 21 Thamotharan Street, Salem, Tamilnadu-636009 Phone: +91-6383437191 Email : ijprtjournal@gmail.com

POLICIES & JOURNAL LINKS

Contact Information

How to cite this article