Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker  for Early Detection of Acute Kidney Injury in Obstructive Uropathy

Muhammad Sajid Akhtar, Arshad Hussain, Fariha Muzammil, Muhammad Nadeem Shafiqu, Irfan Ahmad,Syed Ehsanullah, Farah Naz Tahir

Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker for Early Detection of Acute Kidney Injury in Obstructive Uropathy

Authors

Muhammad Sajid Akhtar, Arshad Hussain, Fariha Muzammil, Muhammad Nadeem Shafiqu, Irfan Ahmad,Syed Ehsanullah, Farah Naz Tahir

Keywords:

NGAL, obstructive uropathy, acute kidney injury, early biomarker, urinary markers.

Abstract

Acute kidney injury (AKI) is a frequent complication of obstructive uropathy, often diagnosed latedue to the limitations of conventional markers such as serum creatinine. Neutrophil GelatinaseAssociated Lipocalin (NGAL) is a promising early biomarker released from injured tubularepithelium. Evaluating its role may provide critical insight into timely diagnosis and intervention.

References

Kablak-Ziembicka A, Przewlocki T. Clinical significance of carotid intima-media complex and carotid plaque assessment by ultrasound for the prediction of adverse cardiovascular events in primary and secondary care patients. J Clin Med. 2021;10(20):4628. DOI: https://doi.org/10.3390/jcm10204628

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Published

2025-05-29

How to Cite

Muhammad Sajid Akhtar, Arshad Hussain, Fariha Muzammil, Muhammad Nadeem Shafiqu, Irfan Ahmad,Syed Ehsanullah, Farah Naz Tahir. (2025). Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker for Early Detection of Acute Kidney Injury in Obstructive Uropathy. International Journal of Pharmacy Research & Technology (IJPRT), 15(1), 1335–1342. Retrieved from https://www.ijprt.org/index.php/pub/article/view/577