Predictive Value of the Systemic Immune-Inflammation Index for Early  Clinical Deterioration in Children Hospitalized With Severe Pneumonia: A  Prospective Cohort Study

Shahzad Mustufa, Ali Akbar Sial, Nimrah Shehzadi, Nayab Ghani,  Qaucea Andleeb, Saima Umar

Predictive Value of the Systemic Immune-Inflammation Index for Early Clinical Deterioration in Children Hospitalized With Severe Pneumonia: A Prospective Cohort Study

Authors

Shahzad Mustufa, Ali Akbar Sial, Nimrah Shehzadi, Nayab Ghani, Qaucea Andleeb, Saima Umar

Keywords:

Systemic immune-inflammation index; Severe pneumonia; Pediatrics; Early clinical deterioration; Intensive care; Biomarkers; Risk stratification.

Abstract

Background:Severe community-acquired pneumonia remains a leading cause of pediatric morbidity andmortality worldwide. Early identification of children at risk for rapid clinical deterioration is essential for timely escalation of care.

References

1. Perin J, Mulick A, Yeung D, et al. Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet Child Adolesc Health. 2022;6(2):106–115. doi:10.1016/S2352-4642(21)00311-4.

Downloads

Published

2026-11-02

How to Cite

Shahzad Mustufa, Ali Akbar Sial, Nimrah Shehzadi, Nayab Ghani, Qaucea Andleeb, Saima Umar. (2026). Predictive Value of the Systemic Immune-Inflammation Index for Early Clinical Deterioration in Children Hospitalized With Severe Pneumonia: A Prospective Cohort Study . International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 7573–7589. Retrieved from https://www.ijprt.org/index.php/pub/article/view/3512