Association of Levodopa Exposure With Impulse-Control Behaviors,  Depression, Anxiety, and Medication Adherence Among Adults With  Parkinson’s Disease: A Cross-Sectional Study

Farkhanda Khan, Junaid Rasool, Samra Sulaiman, Obaid Anwar, Aneel Kumar, Fouzia Perveen

Association of Levodopa Exposure With Impulse-Control Behaviors, Depression, Anxiety, and Medication Adherence Among Adults With Parkinson’s Disease: A Cross-Sectional Study

Authors

Farkhanda Khan, Junaid Rasool, Samra Sulaiman, Obaid Anwar, Aneel Kumar, Fouzia Perveen

Keywords:

Parkinson’s disease; Levodopa equivalent daily dose; Impulse-control behaviors; Depression; Anxiety; Medication adherence; Neuropsychiatry.

Abstract

Background:Levodopa remains the cornerstone ofsymptomatic pharmacotherapy inParkinson’s disease (PD). However,prolonged or high-dose levodopa exposure is increasingly recognized to modulatemesocorticolimbic dopaminergic pathways

References

1. Postuma RB, Berg D, Stern M, et al. MDS clinical diagnostic criteria for Parkinson's disease. Mov Disord. 2015;30(12):15911601. doi:10.1002/mds.26424.

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Published

2026-11-02

How to Cite

Farkhanda Khan, Junaid Rasool, Samra Sulaiman, Obaid Anwar, Aneel Kumar, Fouzia Perveen. (2026). Association of Levodopa Exposure With Impulse-Control Behaviors, Depression, Anxiety, and Medication Adherence Among Adults With Parkinson’s Disease: A Cross-Sectional Study. International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 7547–7559. Retrieved from https://www.ijprt.org/index.php/pub/article/view/3510