Association Between Proton Pump Inhibitor Use and Vitamin B12 Deficiency:  A Cross-Sectional Study

Hassan Liaquat Memon, Shabana Lakho, Anum Siddiqui, Murk Mujahid, Haris Ahmed Shah, Muhammad Yameen Mangan

Association Between Proton Pump Inhibitor Use and Vitamin B12 Deficiency: A Cross-Sectional Study

Authors

Hassan Liaquat Memon, Shabana Lakho, Anum Siddiqui, Murk Mujahid, Haris Ahmed Shah, Muhammad Yameen Mangan

Keywords:

Vitamin B12 deficiency; proton pump inhibitors; gastro-oesophageal reflux disease; PPI use; drug utilisation; nutritional deficiency

Abstract

Background: Vitamin B12 deficiency is acommon nutritional disorder that can resultin neurological and haematologicalcomplications. Proton pump inhibitors(PPIs) are widely used in the management ofgastrointestinal disorders and may interfere with vitamin B12 absorption by suppressing

References

1. Green R, Allen LH, Bjørke-Monsen AL, Brito A, Guéant JL, Miller JW, et al. Vitamin B12 deficiency. Nat Rev Dis Primers. 2017;3:17040.

Downloads

Published

2026-10-19

How to Cite

Hassan Liaquat Memon, Shabana Lakho, Anum Siddiqui, Murk Mujahid, Haris Ahmed Shah, Muhammad Yameen Mangan. (2026). Association Between Proton Pump Inhibitor Use and Vitamin B12 Deficiency: A Cross-Sectional Study. International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 6670–6681. Retrieved from https://www.ijprt.org/index.php/pub/article/view/3383