Effect of Statins on Liver Enzymes and Lipid Profiles in Patients with  Hyperlipidemia: A Biochemical and Physiological Perspective

Jalal Khan, Syeda Tahira Zaidi, Syed Azhar Hussain Zaidi, Muhammad Zarrar Arif ButtIrfan Ahmad, Ambreen Anjum, Farah Naz Tahir

Effect of Statins on Liver Enzymes and Lipid Profiles in Patients with Hyperlipidemia: A Biochemical and Physiological Perspective

Authors

Jalal Khan, Syeda Tahira Zaidi, Syed Azhar Hussain Zaidi, Muhammad Zarrar Arif ButtIrfan Ahmad, Ambreen Anjum, Farah Naz Tahir

Keywords:

Statins, Hyperlipidemia, Liver Enzymes

Abstract

Hyperlipidemia is a significant risk factor for cardiovascular diseases, necessitating effective lipidlowering strategies. Statins, as HMG-CoA reductase inhibitors, are widely prescribed for thispurpose. However, concerns regarding their impact on liver enzymes persist. This study aimed toevaluate the effects of statin therapy on liver function tests and lipid profiles in hyperlipidemicpatients.

References

Pastori D, Pani A, Di Rocco A, et al. Statin liver safety in non-alcoholic fatty liver disease: A systematic review and meta-analysis. Br J Clin Pharmacol. 2022;88(2):441-451. doi:10.1111/bcp.14943

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Published

2025-05-22

How to Cite

Jalal Khan, Syeda Tahira Zaidi, Syed Azhar Hussain Zaidi, Muhammad Zarrar Arif ButtIrfan Ahmad, Ambreen Anjum, Farah Naz Tahir. (2025). Effect of Statins on Liver Enzymes and Lipid Profiles in Patients with Hyperlipidemia: A Biochemical and Physiological Perspective. International Journal of Pharmacy Research & Technology (IJPRT), 15(1), 1350–1356. Retrieved from https://www.ijprt.org/index.php/pub/article/view/579