Pharmacokinetic Variability of Vancomycin Under Different Anesthetic  Conditions in Septic ICU Patients with Augmented Renal Clearance

Muhammad Umer Javaid, Faheed ul Haque, Zain Aamir, Ali Nawaz Bijarani, Sidra Zahid, Nida Ayesha

Pharmacokinetic Variability of Vancomycin Under Different Anesthetic Conditions in Septic ICU Patients with Augmented Renal Clearance

Authors

Muhammad Umer Javaid, Faheed ul Haque, Zain Aamir, Ali Nawaz Bijarani, Sidra Zahid, Nida Ayesha

Keywords:

augmented renal clearance; vancomycin pharmacokinetics; therapeutic drug monitoring

Abstract

Septic critically ill patients exhibiting augmented renal clearance (ARC) present a clinicallyimportant challenge for vancomycin dosing. This prospective observational study evaluated pharmacokinetic variability of vancomycin

References

Tesfamariam NS. The impact of augmented renal clearance on vancomycin pharmacokinetics and pharmacodynamics in critically ill patients. 2024. (PubMed)

Downloads

Published

2025-11-20

How to Cite

Muhammad Umer Javaid, Faheed ul Haque, Zain Aamir, Ali Nawaz Bijarani, Sidra Zahid, Nida Ayesha. (2025). Pharmacokinetic Variability of Vancomycin Under Different Anesthetic Conditions in Septic ICU Patients with Augmented Renal Clearance . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 3400–3409. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1214