E-ISSN 2250-0944 | ISSN 2250-1150
 

Review Article 


Piperine : A Bioenhancer

Amar Singh*, Amar Deep.

Cited by (5)

Abstract
Piperine is a major alkaloid of Pepper fruits belonging to family Piperaceae which has a number of medicinal proper-ties. Pepper fruits are one of them which have been established as bioenhancer for some selected drugs. In Ayureveda since centuries it is called as “Yogvahi”. Black pepper fruits are the supporting evidence where piperine was one of the ingredients of “Trikatu”. Black pepper fruits are used in different food, drink, dessert, perfume as a brandy flavors and preservative of pickles. It is well known as “King of Spices”. Piperine enhances the bioavailability of structurally and therapeutically differ-ent drugs, either by increasing the absorption or by delaying the metabolism of the drug or by a combination of both processes. It is evident that black pepper fruits have been used as bio-enhancer in allopathic system of medicine. Piperine has been used as bioenhancer for certain antibacterial- antibiotics with promising results. The interaction of piperine with drug-metabolizing enzymes is responsible for oxidation, hydroxylation and glucuronidation. Piperine appears to top in the list of bioenhancers as it has been used as bioenhancer for Allopathic, Ayurvedic and Unani drugs. Piperine enhances Cmax of different drugs significantly.

Key words: Black Pepper, Bio-enhancer, Trikatu, Piper nigrum, Piperine


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Singh A, Deep A. Piperine : A Bioenhancer. IJPRT. 2011; 1(1): 1-5. doi:10.31838/ijprt/01.01.01


Web Style

Singh A, Deep A. Piperine : A Bioenhancer. https://www.ijprt.org/?mno=302643665 [Access: June 25, 2022]. doi:10.31838/ijprt/01.01.01


AMA (American Medical Association) Style

Singh A, Deep A. Piperine : A Bioenhancer. IJPRT. 2011; 1(1): 1-5. doi:10.31838/ijprt/01.01.01



Vancouver/ICMJE Style

Singh A, Deep A. Piperine : A Bioenhancer. IJPRT. (2011), [cited June 25, 2022]; 1(1): 1-5. doi:10.31838/ijprt/01.01.01



Harvard Style

Singh, A. & Deep, . A. (2011) Piperine : A Bioenhancer. IJPRT, 1 (1), 1-5. doi:10.31838/ijprt/01.01.01



Turabian Style

Singh, Amar, and Amar Deep. 2011. Piperine : A Bioenhancer. International Journal of Pharmacy Research & Technology, 1 (1), 1-5. doi:10.31838/ijprt/01.01.01



Chicago Style

Singh, Amar, and Amar Deep. "Piperine : A Bioenhancer." International Journal of Pharmacy Research & Technology 1 (2011), 1-5. doi:10.31838/ijprt/01.01.01



MLA (The Modern Language Association) Style

Singh, Amar, and Amar Deep. "Piperine : A Bioenhancer." International Journal of Pharmacy Research & Technology 1.1 (2011), 1-5. Print. doi:10.31838/ijprt/01.01.01



APA (American Psychological Association) Style

Singh, A. & Deep, . A. (2011) Piperine : A Bioenhancer. International Journal of Pharmacy Research & Technology, 1 (1), 1-5. doi:10.31838/ijprt/01.01.01





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