Histological Alterations in Bronchial Epithelium and Serum IgE in Bronchial  Asthma

Saira Aslam, Uzma Hanif, Sadia Saqib, Ahmad Farzad Qureshi, Amrat, Kanwal Khalid

Histological Alterations in Bronchial Epithelium and Serum IgE in Bronchial Asthma

Authors

Saira Aslam, Uzma Hanif, Sadia Saqib, Ahmad Farzad Qureshi, Amrat, Kanwal Khalid

Keywords:

Bronchial asthma; bronchial epithelium; histology; serum IgE; airway remodeling; goblet cell hyperplasia; basement membrane thickening

Abstract

A prospective cross-sectional study assessed histological alterations in bronchial epithelium andtheir correlation with serum total IgE in 120 adult patients with bronchial asthma compared to 60healthy controls. Bronchial biopsies obtained via bronchoscopy were evaluated for epithelialshedding, goblet cell hyperplasia

References

Bhattarai, N., & Basnet, S. (2021). Airway remodeling and asthma severity in adults: histological perspectives. Respiratory Pathology Insights, 10(3), 193–202.

Chen, W., et al. (2022). Serum IgE correlates with airway structural changes in allergic asthma. Journal of Asthma Research, 14(2), 89–98.

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Published

2025-08-25

How to Cite

Saira Aslam, Uzma Hanif, Sadia Saqib, Ahmad Farzad Qureshi, Amrat, Kanwal Khalid. (2025). Histological Alterations in Bronchial Epithelium and Serum IgE in Bronchial Asthma. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 1503–1508. Retrieved from https://www.ijprt.org/index.php/pub/article/view/918