Biochemical, Microbiological, and Physiological Markers of NAFLD in  Obesity: The Role of GGT, Ferritin, and Gut Microbial Dysbiosis, Including  LPS-Producing Bacteria and SCFA Alterations

Bilal Ilyas, Mahwish Shahzad, Sardar Ahmad, Mariam Danish Iqbal, Aisha Liaqat, Sonia Tahir

Biochemical, Microbiological, and Physiological Markers of NAFLD in Obesity: The Role of GGT, Ferritin, and Gut Microbial Dysbiosis, Including LPS-Producing Bacteria and SCFA Alterations

Authors

Bilal Ilyas, Mahwish Shahzad, Sardar Ahmad, Mariam Danish Iqbal, Aisha Liaqat, Sonia Tahir

Keywords:

nonalcoholic fatty liver disease; gamma-glutamyl transferase; ferritin; gut microbiota; lipopolysaccharide; short-chain fatty acids

Abstract

Evaluation of gamma-glutamyl transferase (GGT), serum ferritin, and specific gut microbiomealterations—including lipopolysaccharide (LPS)-producing bacteria and short-chain fatty acid(SCFA) profiles—was conducted in obese individuals to identify biomarkers predictive of nonalcoholic fatty liver disease (NAFLD).

References

García-Carvajal, C. A., et al. (2023). Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome. Journal of Hepatology Research, 45(2), 123–134.

Huang, Y., et al. (2021). Compositional alterations of gut microbiota in nonalcoholic fatty liver disease patients: A systematic review and meta-analysis. Microbiome Research, 9(1), 15–27.

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Published

2025-08-25

How to Cite

Bilal Ilyas, Mahwish Shahzad, Sardar Ahmad, Mariam Danish Iqbal, Aisha Liaqat, Sonia Tahir. (2025). Biochemical, Microbiological, and Physiological Markers of NAFLD in Obesity: The Role of GGT, Ferritin, and Gut Microbial Dysbiosis, Including LPS-Producing Bacteria and SCFA Alterations . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 1477–1484. Retrieved from https://www.ijprt.org/index.php/pub/article/view/915