0.5% CARBOXYMETHYLCELLULOSE VERSUS 0.4%POLYETHYLENE  GLYCOL / 0.3% PROPYLENE GLYCOL AS TEAR SUBSTITUTES FOR  THE TREATMENT OF DRY EYE

Dr Shweta Sinha ,Dr Ritu Jain

0.5% CARBOXYMETHYLCELLULOSE VERSUS 0.4%POLYETHYLENE GLYCOL / 0.3% PROPYLENE GLYCOL AS TEAR SUBSTITUTES FOR THE TREATMENT OF DRY EYE

Authors

Dr Shweta Sinha ,Dr Ritu Jain

Keywords:

Dry Eye Disease, Carboxymethylcellulose, Polyethylene Glycol, Propylene Glycol, OSDI, TBUT, Schirmer’s Test

Abstract

Background: Dry eye disease (DED) is a multifactorial disorder characterized by tear filminstability, ocular surface inflammation, and discomfort, leading to impaired vision and qualityof life. Artificial tear substitutes are the cornerstone of management, with
Carboxymethylcellulose (CMC) and Polyethylene Glycol/Propylene Glycol (PEG/PG) beingwidely used.
Objective: To compare the efficacy of 0.5% CMC and 0.4% PEG/0.3% PG eye drops in patientswith mild to moderate DED.

References

Stapleton F, Alves M, Bunya VY, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334-65.

Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017;15(3):276-83.

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Published

2025-08-23

How to Cite

Dr Shweta Sinha ,Dr Ritu Jain. (2025). 0.5% CARBOXYMETHYLCELLULOSE VERSUS 0.4%POLYETHYLENE GLYCOL / 0.3% PROPYLENE GLYCOL AS TEAR SUBSTITUTES FOR THE TREATMENT OF DRY EYE . International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 1428–1440. Retrieved from https://www.ijprt.org/index.php/pub/article/view/909