Comparative Efficacy of Intranasal Corticosteroids vs. Antihistamines in Allergic Rhinitis: A Randomized Biochemical-Based Study

Waqas Javaid, Muhammad Usman Khalid Amin, Saleha Safdar, Ziaullah, Ghulam Dastgir Khan, Muhammad Naeem

Comparative Efficacy of Intranasal Corticosteroids vs. Antihistamines in Allergic Rhinitis: A Randomized Biochemical-Based Study

Authors

Waqas Javaid, Muhammad Usman Khalid Amin, Saleha Safdar, Ziaullah, Ghulam Dastgir Khan, Muhammad Naeem

Keywords:

allergic rhinitis, intranasal corticosteroids, antihistamine, eosinophil cationic protein, interleukin-4, immunoglobulin E

Abstract

Allergic rhinitis (AR) significantly impairs quality of life and presents with chronic nasalinflammation. This randomized open-label study compared intranasal corticosteroids (INCS) andoral second-generation antihistamines (AH) in 120 adult patients over 8 weeks

References

Brożek, J. L., Bousquet, J., Baena-Cagnani, C. E., et al. (2020). Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines — 2020 revision. Journal of Allergy and Clinical Immunology, 146(4), 763–775. https://doi.org/10.1016/j.jaci.2020.05.019

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Published

2025-07-19

How to Cite

Waqas Javaid, Muhammad Usman Khalid Amin, Saleha Safdar, Ziaullah, Ghulam Dastgir Khan, Muhammad Naeem. (2025). Comparative Efficacy of Intranasal Corticosteroids vs. Antihistamines in Allergic Rhinitis: A Randomized Biochemical-Based Study. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 484–489. Retrieved from https://www.ijprt.org/index.php/pub/article/view/733