Electroporation: An Emerging Technique For Drug Delivery

Abstract

STRACT Electroporation is an emerging field in delivery of drugs into the body by any medium or vector. Now a day, it is widely used in many routes for the treatment of diseases. Electroporation is a process in which an electric field is applied to the living cell which results in formation of pores in cell. In this method, viruses or plasmids enter into the cell in the form of vector. For this method instruments like Eppendorf Eporator are used to provide a fast, simple and safe path to administer bacteria, yeast or any other micro-organism as a vector inside the body with DNA/RNA. This technique offers a large number of applications in various fields such as DNA transformation, induced cell diffusion, in transdermal drug delivery, chemotherapy, gene therapy etc. This review deals with the applications, recent developments future scenario of this process. Electroporation knife is the latest invention used to kill the cancer tumors. Feasibility of transdermal electroporation for insulin loaded nanocarriers is another achievement. This approach may also use in nuclear targeting. Countless researches still going on to produce an efficient, safe and simple process for treatment of diseases and provide a better future to the human beings.