Association of Vitamin B12 Status, Peripheral Neuropathy Severity, and  Cognitive Performance in Patients With Type 2 Diabetes Mellitus: A Cross Sectional Study

Iqra Riaz, Sharaf Ali, Muhammad Mohsin Naseer, Mohammad Muaz Rehman, Sehar Afreen, Fatmakhatun Doi

Association of Vitamin B12 Status, Peripheral Neuropathy Severity, and Cognitive Performance in Patients With Type 2 Diabetes Mellitus: A Cross Sectional Study

Authors

Iqra Riaz, Sharaf Ali, Muhammad Mohsin Naseer, Mohammad Muaz Rehman, Sehar Afreen, Fatmakhatun Doi

Keywords:

Vitamin B12; type 2 diabetes mellitus; peripheral neuropathy; cognitive performance; metformin; HbA1c; neurological complications.

Abstract

Background: Vitamin B12 deficiency is apotentially reversible nutritional abnormalitythat may contribute to neurologicaldysfunction. Patients with type 2 diabetes mellitus (T2DM) are at risk of peripheralneuropathy and cognitive impairment

References

1. Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med. 1998;339(4):229–234. doi:10.1056/NEJM199807233390404.

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Published

2026-10-24

How to Cite

Iqra Riaz, Sharaf Ali, Muhammad Mohsin Naseer, Mohammad Muaz Rehman, Sehar Afreen, Fatmakhatun Doi. (2026). Association of Vitamin B12 Status, Peripheral Neuropathy Severity, and Cognitive Performance in Patients With Type 2 Diabetes Mellitus: A Cross Sectional Study. International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 6960–6970. Retrieved from https://www.ijprt.org/index.php/pub/article/view/3433