Association of Antiseizure Pharmacotherapy and Psychiatric Comorbidities  With Mental Health and Quality of Life in Adults With Drug-Resistant  Epilepsy: A Cross-Sectional Study

Junaid Rasool, Amna Riaz, Mahrukh Ansar, Anika Idnan, Sehrish Mahmood, Shahana Rehman

Association of Antiseizure Pharmacotherapy and Psychiatric Comorbidities With Mental Health and Quality of Life in Adults With Drug-Resistant Epilepsy: A Cross-Sectional Study

Authors

Junaid Rasool, Amna Riaz, Mahrukh Ansar, Anika Idnan, Sehrish Mahmood, Shahana Rehman

Keywords:

Drug-resistant antiseizure medications; epilepsy; polytherapy; depression; anxiety; quality of life;QOLIE 31;PHQ-9;GAD-7;epilepsy pharmacotherapy.

Abstract

Background: Drug-resistant epilepsy isassociated with persistent seizures, treatmentburden, psychiatric comorbidities,medication-related adverse effects, and impaired quality of life. Although antiseizuremedications (ASMs) remain the cornerstone

References

1. Scheffer IE, Berkovic S, Capovilla G, et al. ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology. Epilepsia. 2017;58(4):512–521.

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Published

2026-10-15

How to Cite

Junaid Rasool, Amna Riaz, Mahrukh Ansar, Anika Idnan, Sehrish Mahmood, Shahana Rehman. (2026). Association of Antiseizure Pharmacotherapy and Psychiatric Comorbidities With Mental Health and Quality of Life in Adults With Drug-Resistant Epilepsy: A Cross-Sectional Study . International Journal of Pharmacy Research & Technology (IJPRT), 16(2), 6448–6458. Retrieved from https://www.ijprt.org/index.php/pub/article/view/3357