Serum Ferritin and Oxidative Stress Markers as Indicators of Disease Progression in Chronic Liver Disease.

Authors

  • Abdul Aziz, Tuba Azam, Sohaib Farooq, Zahid Rashid, Muhammad Adnan Sadiq, Ambreen Zeeshan, Hawaida Khan

Keywords:

ferritin; oxidative stress; chronic liver disease.

Abstract

Serum ferritin has emerged as a marker of iron storage and inflammation, while oxidative stress is increasingly implicated in hepatic injury and fibrosis advancement. This case-control observational study aimed to evaluate the relationship between serum ferritin, selected oxidative stress markers (malondialdehyde [MDA], protein carbonyls [PC], total antioxidant capacity [TAC]), and disease severity in patients with chronic liver disease (CLD).

References

Nguyen VH, et al. Iron overload biomarkers and fibrosis progression in non-alcoholic steatohepatitis: a systematic evaluation. Hepatol Res. 2023;53(6):622-633.

Zhao J, et al. Elevated serum ferritin predicts worse outcomes in patients with cirrhosis: a prospective cohort study. Liver Int. 2024;44(3):567-576

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Published

2025-10-28

How to Cite

Abdul Aziz, Tuba Azam, Sohaib Farooq, Zahid Rashid, Muhammad Adnan Sadiq, Ambreen Zeeshan, Hawaida Khan. (2025). Serum Ferritin and Oxidative Stress Markers as Indicators of Disease Progression in Chronic Liver Disease. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2853–2861. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1126

Issue

Section

Research Article