Correlation of Serum CA-125 Levels with Ultrasound Doppler Indices in Ovarian Neoplasms

Authors

  • Sehrish Sabir, Aassia Fazal, Yamna Sabahat Chaudhry, Shazia Aman, Humna Ashraf, Azqa Zafar

Keywords:

CA-125; Doppler ultrasound; ovarian neoplasms; resistance index; pulsatility index

Abstract

Elevated serum CA-125 is widely used in the assessment of ovarian neoplasms, while Doppler ultrasonography provides dynamic vascular information potentially reflective of malignant transformation. The present case-control study aimed to evaluate the correlation between preoperative serum CA-125 levels and colour-Doppler ultrasound indices (resistance index [RI], pulsatility index [PI], peak systolic velocity [PSV]) in women with ovarian tumors and to determine their combined value in distinguishing benign from malignant lesions.

References

Xun L, Huang C, Tang Y, et al. Utility of conventional ultrasound, Doppler ultrasound and contrast-enhanced ultrasound in differentiating benign and malignant ovarian masses: a systematic review and meta-analysis. BMJ Open. 2021. (BMJ Open)

Liberto JM, Quinn MA, et al. Current and emerging methods for ovarian cancer detection and characterization: role of ultrasound and biomarkers. Review Article. 2022. (PubMed Central)

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Published

2025-10-28

How to Cite

Sehrish Sabir, Aassia Fazal, Yamna Sabahat Chaudhry, Shazia Aman, Humna Ashraf, Azqa Zafar. (2025). Correlation of Serum CA-125 Levels with Ultrasound Doppler Indices in Ovarian Neoplasms. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2818–2825. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1122

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Section

Research Article