Assessment of Serum Alpha-Fetoprotein, Triphasic CT, and Renal Parameters in the Early Detection of Hepatocellular Carcinoma
Keywords:
alpha-fetoprotein; hepatocellular carcinoma; triphasic CT; renal parameters; albuminuria.Abstract
Early detection of hepatocellular carcinoma (HCC) remains critical to enable curative therapies and improve survival. The present case-control study evaluates three modalities—serum alphafetoprotein (AFP), triphasic computed tomography (CT) imaging, and selected renal parameters (serum creatinine, estimated glomerular filtration rate [eGFR], and albuminuria)—for their utility in identifying early-stage HCC among high-risk patients with chronic liver disease.
References
Tzartzeva K, Obi J, Rich NE, et al. Surveillance imaging and alpha-fetoprotein for early detection of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis.Gastroenterology. 2018;154(6):1706-1718.e1. (PubMed Central)
Daif A, Al-Azzawi MA, Sakr MA, Ismail HA, Gadallah M. Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients. J Egypt Natl Canc Inst. 2023;35:11. (SpringerOpen)
 
						




