Evaluation of serum ammonia and inflammatory markers in patients with hepatic encephalopathy

Hassan Safdar, Sidra Latif, Zahid Rashid, Amin Anjum, Shazia Hameed, Jackson Pereketya

Evaluation of serum ammonia and inflammatory markers in patients with hepatic encephalopathy

Authors

Hassan Safdar, Sidra Latif, Zahid Rashid, Amin Anjum, Shazia Hameed, Jackson Pereketya

Keywords:

Hepatic encephalopathy, serum ammonia, C-reactive protein, interleukin-6

Abstract

Hepatic encephalopathy (HE) is a complex neuropsychiatric syndrome resulting from liver dysfunction and portal-systemic shunting, with hyperammonemia and systemic inflammation playing critical roles in its pathogenesis. This study aimed to evaluate serum ammonia levels and inflammatory markers, including C-reactive protein (CRP) and interleukin-6 (IL-6), in patients with hepatic encephalopathy.

References

Kablak-Ziembicka A, et al. Clinical significance of serum ammonia in hepatic encephalopathy. J Clin Med. 2022;11(5):1342.

Przewlocki T, et al. Systemic inflammation and its role in hepatic encephalopathy. World J Hepatol. 2023;15(2):85-98.

Downloads

Published

2025-10-28

How to Cite

Hassan Safdar, Sidra Latif, Zahid Rashid, Amin Anjum, Shazia Hameed, Jackson Pereketya. (2025). Evaluation of serum ammonia and inflammatory markers in patients with hepatic encephalopathy. International Journal of Pharmacy Research & Technology (IJPRT), 15(2), 2786–2792. Retrieved from https://www.ijprt.org/index.php/pub/article/view/1120